Research evidence
Pinhole, CO2 fractional, R-Zero PFD — built on 150+ papers published in US/EU dermatology societies and SCI journals over 20 years.
PN (polynucleotide) purified from salmon DNA is injected directly into the skin. It is reported to be well tolerated by human tissue, and its DNA chains are longer than those of PDRN, so it stays in the skin longer.
Pinhole Technique In-house technique combining CO2/Er:YAG laser with the pinhole approach. Applied to burn, surgical, self-inflicted, acne, and varicella scars. Case series and clinical studies published 2006–2014 in Journal of Dermatology, Dermatologic Surgery, and more.
Photothermal action through the nail plate A 1064 nm Nd:YAG laser passes through the nail plate and carries heat to the tissue beneath. It raises the temperature where the fungus sits without filing the nail away, and is combined with antifungal medication where indicated.
Targeted injection
Micro-injection A negative-pressure multi-needle injector places hyaluronic acid and regenerative ingredients into the dermis, supporting elasticity and slowing visible ageing over the medium term. Less product is lost than with hand injection and it spreads evenly within the dermis, so the effect lasts longer.